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Viral Vector Scientist (JP7676)

Thousand Oaks, ca · Biotech/Pharmaceutical
Job Title: Viral Vector Scientist (JP7676)
Location: Thousand Oaks, CA    
Employment Type: Contract
Business Unit: Cellular Sciences
Duration: 12 months with likely extensions
Job posting date: 10 September 2020
Note: Essential worker working on site 50% of the time
 
 
3 Key Consulting is hiring a Scientist for a consulting engagement with our direct client, a leading global bio-pharmaceutical company.
 
Job Summary:

The Viral Vector Scientist will be responsible for participating in viral vector process and/or analytical development. The position will be part of a dynamic and growing viral vector team based in Thousand Oaks.

Basic Qualifications
Doctorate degree and 0-3 years of industry-related experience OR Master’s degree and 3+ years industry-related experience OR Bachelor’s degree and 5+ years industry-related experience

Preferred Qualifications

Experience:
  • A Master's or Doctorate degree in Biological Sciences or a related field
  • 5+ years of experience with mammalian cell culture, bioreactors, and bioassay technology
  • Experience in biotechnology or a related industry with a track record of strong scientific contributions and project leadership.
  • Demonstrated ability to independently identify, develop, and implement problem-solving approaches using the scientific method.
  • Ability to develop and apply methodology and platform approaches and utilize superior problem-solving skills as well as out-of-the-box thinking to contribute to technology improvements.
  • Demonstrated in-depth knowledge of laboratory equipment and operations.
  • Demonstrated superior communication and scientific writing skills.
  • Ability to execute complex and cutting-edge projects as part of a team or independently.

    Knowledge:
  • Knowledge of mammalian cell culture, media and transfection reagent formulation, bioreactors, and virus analytical methods.
  • Knowledge and experience with virus culture at Biosafety Level 2 and 2+ and applicable safety standards.
  • Knowledge and experience with experimental planning and statistical analysis, such as Design of Experiment (DOE), process design, characterization, and optimization.
  • Knowledge and experience with infectious and physical titer methods and process residual and impurity assays.
  • Knowledge and experience with mammalian cell culture scale-up and bioreactor selection, operation, and engineering principles.
  • Knowledge with processes involved in viral vector GMP manufacturing, characterization and release testing, and QA/QC.
  • Knowledge and experience working with hazardous compounds and chemicals.
  • Ability to evaluate documentation/operations according to company procedures.
  • Ability to make decisions in a timely and thoughtful manner, taking in consideration available information.
  • Ability to respond appropriately if a situation requires a different set of skills and work approaches.
  • Ability to meet expectations and requirements of internal and external customers.
  • Ability to assimilate information and make timely decisions that impact the functional area.

    Skills:
  • Aseptic technique skills.
  • Mammalian cell culture skills.
  • Virology skills.
  • Analytical testing skills.
  • Problem solving skills.
  • Technical writing skills for protocols, SOPs, reports, and presentations.
  • Communication (verbal and written) at all levels.
  • Statistical analysis tools to perform data analysis and evaluation.
  • Investigation skills.
  • Presentation skills.
  • Negotiation skills.

    Competencies:
  • Related process development or research experience in the biotechnology industry and/or academia.
  • Attention and dedication to process and method development.
  • Must be a team player.
  • Ability to organize work, handle multiple priorities, and meet deadlines.
  • Must be flexible and adaptable to changing priorities and requirements.
  • Demonstrates understanding of when and how to appropriately escalate.
  • Participates in and can direct team efforts to advance development/technology programs within the department.
  • Applies team experiences to facilitate cohesiveness and build team spirit.
  • Independently authors technical reports and assessments.
  • Capable of organizing and conducting effective meetings.
  • Learns and applies facilitation and listening skills.
  • Identifies resources and develops timelines for project activities.
  • Organizes, plans, and controls multiple project activities to meet corporate timelines.

Top Must have Skill Sets:
  • Mammalian cell bioreactor development (sub-set of cell culture) (expert level)
  • Analytical testing of viral vectors (expert level).
  • Soft Skills-initiative, teamwork, and independent thinking.
 
Day-To-Day Responsibilities:
  • This role will design and perform bioreactor studies to support development of robust viral vector platforms. Responsibilities include process transfer, cell line testing, growth and production optimization, scale up, and process characterization, in order to improve robustness and understanding of operating and performance parameters.
  • The role will draft and deliver protocols, SOPs, and document results in technical reports and presentations to support viral vector process development. He/she will collaborate closely with colleagues inside and outside the team and with external partners.
  • The role will also perform analytical tests to support the upstream and downstream viral vector process efforts. Depending on the candidate’s skill set, this may include development of analytical assays, such as residual host cell protein, residual host cell DNA impurities, and virus infectious and particle titer assays, and shepherding those methods through transfer to QC.
Employee Value Proposition:
Working with a growing and dynamic team, access to resources who are doing cutting edge projects, growing their skill set within the project.
 
Red Flags:
Lack of cell culture and hands-on laboratory experience.
 
Interview Process: phone/skype. 
 
We invite qualified candidates to send your resume to resumes@3keyconsulting.com. If you decide that you’re not interested in pursuing this position, please feel free to look at other positions on our website www.3keyconsulting.com. You are welcome to also share this posting with anyone you think might be interested in applying for this role.
 
 
 
 
 
Regards,
 
3KC Talent Acquisition Team
 
 

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