3 Key Consulting is hiring an entry level Associate Scientist for a consulting engagement with our direct client, a leading global biopharmaceutical company.
Job Description/Responsibilities: The role is to provide process development lab support to process development operations for support and lifecycle development of a viral product.
Roles for the scientist include:
Production of live viruses at both bench and pilot manufacturing scales
Support for a GMP manufacturing process
Development of novel mammalian cell culture and next generation purification steps to increase yield and process robustness
The role is placed in Cambridge, MA (AMA) Oncolytic Virus PD team and will report directly to the PD Principal Scientist for this team.
The successful candidate will apply fundamental scientific principles to Biopharmaceutical manufacturing processes (upstream cell culture and downstream purification) including:
A good understanding of mammalian cell culture processes; bioreactors, metabolism profiling, influence of raw material attributes and aseptic handling.
A good understanding of chromatography, ultrafiltration and normal flow filtration operations.
Familiarity with chemical engineering principles for the scale up of unit operations from bench scale to commercial scale. Understanding process capabilities and means to achieve yield optimizations and increased efficiencies.
0-2 years of experience in a Biotech/Pharma Process Development and/or Manufacturing Support role for drug substance manufacturing.
Recent graduates from scientific background welcomed
Able to apply engineering principles and statistical analysis, including design of experiments, in-order to solve processing issues and evaluate opportunities for process improvements
Excellent written and verbal communication
Ability to work under moderate direction.
Able to analyze and interpret data
Be a self-starter with the ability to take on several projects at one time Experience of GMP documentation and principles
Education: Bachelors Degree in Science related field
Top Must-Have Skill Sets:
Experience at cell culture operations, preferably mammalian cell culture (0-2 years experience)
Understanding of GMPs, preferably having worked to GMP standards previously (0-2 years of experience)
Statistic/chromatography exposure (0-2 years of experience) a plus
soft skills: Ability to work and plan work independently, and maintain documentation e.g. lab notebooks in a contemporaneous manner
Technical writing (plus, not required)
Day to day responsibilities:
Cell culture operations to support pilot scale batch production and scale-down lab studies
Preparation and performance of purification methods e.g. Ultrafiltration, Chromatography (incl column packing), filtration
Routine periodic equipment maintenance e.g. cell counter calibrations, equipment cleans
Employee Value Proposition: The person in this role will work with a virus therapy. This is one of the most unique items in company's portfolio. This lab will have some cutting-edge work. This product is the only one of it's kind that is approved by the FDA. You will also learn statistics. Red Flags: 1. Candidates with solely analytical method or chemistry experience and therefore limited transferable skills 2. jumpy resume Interview process:
We invite qualified candidates to send your resume to email@example.com. If you decide that you’re not interested in pursuing this position, please feel free to take a look at the other positions on our website www.3keyconsulting.com/careers. You are welcome to also share this opportunity with anyone you think might be interested in applying for this role.