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Senior Associate, Biophysical Characterization of Proteins – (JP9919)

Thousand Oaks, CA · Biotech/Pharmaceutical
Job Title:  Senior Associate, Biophysical Characterization of Proteins – (JP9919)
Location: Thousand Oaks, CA.
Employment Type:  Contract
Business Unit: Biological Relevance and Charactization
Duration: 1+ years (with likely extensions)
Notes:  100% onsite. Local candidate. $24 - $28 per hour.

Posting Date:  03/08/2022

3 Key Consulting is hiring a Senior Associate for a consulting engagement with our direct client, a leading global biopharmaceutical company.

Job Description:
The successful candidate will perform sample preparation, testing, methods development, and characterization particularly for the assessment of the molecular weight of size variants by either SEC-MALS (HPLC coupled with light scattering detection) or AUC (analytical ultracentrifugation) for biopharmaceutical products. Activities could also include the characterizing of higher order structure by spectroscopic techniques such as FTIR, Circular dichroism or DSC. The overall objective will be to support comparability and similarity studies, technology development efforts, and non-routine investigations. Other duties include sample preparation, complex data analyses, generation of technical documents and technical presentations, and setting of acceptance criteria in support of process development, process/method transfers, and comparability/similarity studies. The position requires demonstrated ability to work collaboratively with other scientists, and to have the capacity to be flexible and adaptive to changing priorities.

Why is the Position Open?
backfill; one person left a month ago.

Top Must-Have Skill Sets:
  • Two or more years of experience directly related to biophysical characterization for protein drug products.
  • Hand-on experience with HPLC systems and analytical ultracentrifugation for the separation and characterization of size variants.
  • Strong laboratory analytical skills, including routine testing as well as the design and execution of scientific experiments and interpretation of results.
  • Experience in lab notebooks, reporting, data verify.

Day to Day Responsibilities:
The successful candidate will perform sample preparation, testing, methods development and characterization particularly for the assessment of the molecular weight of size variants by either SEC-MALS (HPLC coupled with light scattering detection) or AUC (analytical ultracentrifugation) for biopharmaceutical products. Activities could also include the characterizing of higher order structure by spectroscopic techniques such as FTIR, Circular dichroism or DSC.

Basic Qualifications:
  • M.S degree in Chemistry, Biochemistry, Biotechnology, Physics or related discipline, OR
  • B.S. degree in Chemistry, Biochemistry, Biotechnology, Chemical Engineering, Physics or related discipline with 3+ years work experience in the biopharmaceutical industry.

Preferred Qualifications:
  • Two or more years of experience directly related to biophysical characterization in protein drug products, including the use of spectroscopic techniques such as FTIR, CD, and NMR spectroscopy for protein structure analysis.
  • Hand-on experience with HPLC systems and analytical ultracentrifugation for the separation and characterization of size variants.
  • Application of calorimetric methods such as DSC for thermal stability analysis.
  • Strong laboratory analytical skills, including routine testing as well as the design and execution of scientific experiments and interpretation of results.
  • Experience developing, qualifying, and/or validating analytical methods, analyzing data, and setting acceptance criteria to support product comparability/similarity studies.
  • Demonstrated ability to work collaboratively with other scientists on multidisciplinary, cross-functional teams.

Red Flags:
  • Lack of experience in HPLC, protein-based lab work.
  • No lab experience.

Interview process:
Phone screening followed by in-person interview.



We invite qualified candidates to send your resume to resumes@3keyconsulting.com.  If you decide that you’re not interested in pursuing this particular position, please feel free to take a look at the other positions on our website www.3keyconsulting.com/careers. You are also welcome to share this opportunity with anyone you think might be interested in applying for this role.
 
 
Regards,
 
3KC Talent Acquisition Team
 
 
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