Job Title:   Associate Scientist - (JP9818)
Location: Thousand Oaks, CA.
Employment Type:  Contract
Business Unit: Drug Substance Technologies
Duration: 2+ years (with likely extensions and/or conversion to permanent)
Posting Date: 2/16/2022
Notes: 100% onsite; must have Bachelor’s degree in Chemistry or Chemical Engineering

3 Key Consulting is hiring an Associate Scientist for a consulting engagement with our direct client, a leading global biopharmaceutical company.

Job Description:
We are seeking a highly motivated individual to assist in our high-throughput experimentation (HTE) group and to support synthetics process development in Thousand Oaks, CA. The candidate will work closely with our process chemists/chemical engineers to conduct high-throughput experiments and to assist with analytical data processing for high-throughput experiments. In addition to high-throughput support, the position will support the execution of pressurized reactions reactors ranging from 0.0-5 mL to 5 L scales.

Support High-Throughput Experimentation in Synthetics Process Development:
 

• Collaborate with process chemists/chemical engineers to execute and analyze high-throughput parallel experimentation (HTE) studies for the following:
  • Reaction screening/optimization for chemical reactions (catalysis, biocatalysis, and non-catalytic transformations).
  • Pressurized gas reactions.
  • Organic solvent extraction studies.
  • Metal scavenger/ remediation screenings.
  • Solubility studies of drug substance intermediates.
  • Crystallization studies of drug substances intermediates
• Use various automation and analytical software/hardware to support THE.
• Maintain good laboratory documentation practices and compliance with electronic laboratory notebook (ELN) guidelines

Laboratory Housekeeping/Management:
 

• Coordinate with third-party vendors and our laboratory asset management service (LAMP) for preventative maintenance, calibration, and repair service of equipment and instruments
• Initiate work orders when necessary to assist with set-up of new equipment and/or remove obsolete/life-cycled equipment
• Clean/decontaminate equipment and hood surfaces contaminated with hazardous materials
• Maintain laboratory equipment and order replacement or add-on parts/accessories as needed
• Contact third-party vendors for information and quotes
• Evaluate and document performance and reliability of lab equipment
• Manage solid and liquid waste within synthetic laboratories per guidelines
• Handle incoming/outgoing shipments of tools, ancillary processing equipment and consumables and chemicals to remote client sites
• Maintain good laboratory housekeeping and adhere to established organizational principles

Chemical Library Maintenance:
 

• Order and organize laboratory reagents and consumables to support high-throughput experimentation
• Ensure chemical library maintenance and re-order chemicals as needed
• Maintain and update list of chemical inventories and ensure that the chemical and reagent inventory system (CRIS) is up to date.

Top Must Have Skills:

• At least 1 year of research experience in chemistry laboratory.

• Computer proficiency.
• Must have Bachelor’s degree in Chemistry or Chemical Engineering.

Day to Day Responsibilities:

• Follow procedure and perform laboratory experiments.
• Maintain detailed records in electronic laboratory notebook.
• Maintain chemical inventory and order chemicals as needed.
• Organize laboratory space by following 5S.

Basic Qualifications:

• Bachelor’s degree in chemistry or chemical engineering and experience in laboratory or manufacturing setting (academia or industry)
• Strong scientific aptitude; attention to detail; technical problem-solving skills; and ability to multi-task
• Familiarity with good laboratory notebook documentation
• Trained in basic laboratory safety

Preferred Qualifications:

• Master’s degree in chemistry or chemical engineering.
• Academic and/or industrial experience working in a organic chemistry or chemical engineering laboratory.
• Familiarity with automation, computational chemistry and/or data analytics software such as LEA, Spotfire, Gaussian, and Dynochem.
• Familiarity with analytical instrumentation including HPLC, GC, and NMR spectroscopy.

Red Flags:

• No laboratory experience.
• Needs US Visa sponsorship.
• Not available to work 5 days/week on-site.

Interview process:
1 h video interview with 10 min research talk by candidate

We invite qualified candidates to send your resume to resumes@3keyconsulting.com.  If you decide that you’re not interested in pursuing this particular position, please feel free to take a look at the other positions on our website www.3keyconsulting.com/careers. You are also welcome to share this opportunity with anyone you think might be interested in applying for this role.