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Senior Research Associate (JP8365)

South San Francisco, CA · Biotech/Pharmaceutical
Job Title:  Senior Research Associate (JP8365)
Location: South San Francisco, CA. (Onsite Essential)
Employment Type:  Contract
Business Unit: Biologics and Protein Technologies
Duration: 1+ years (with likely extensions)
Posting Date: 3/12/21
3 Key Consulting is hiring an Senior Research Associate for a consulting engagement with our direct client, a leading global biopharmaceutical company.
Job Description:
Only candidates with biochemistry experience need apply.  Client is a leading global biotechnology company, with a mission to serve patients around the world.   Client is hiring in the Department of Protein Technologies, Biologics, at their Research and Development facility in South San Francisco, CA.
We are looking for a highly motivated candidate to join the ASF Protein Technologies group. This group provides comprehensive molecular cloning, protein expression, purification and analytics support for the early-stage pipeline of projects including both protein and small molecule therapeutics. The successful candidate will be a part of a team supporting lead identification of therapeutic proteins and protein reagent production for client Research.
Why is the Position Open?
Supplement additional workload on team.
Top Must-Have Skill Sets:
  • Protein purification
  • Protein analytics
  • Good organization skills
Day to Day Responsibilities:
Job Duties: Candidate will work in a highly-integrated and collaborative team environment and contribute independently to diverse functions depending upon project needs and priority.
1. Protein purification
a) Purifying mammalian cell-expressed proteins using Akta chromatography system (including affinity purification, ion exchange, and size-exclusion chromatography).
b) Removal of protein tags using proteases; biotinylation of proteins, as needed.
2. Protein Analytics
a) SDS-PAGE, Western blotting
b) HPLC-SEC analytics of purified proteins and data interpretation
c) Mass Spectrometry analytics of purified proteins and data interpretation
3. General routine laboratory activities
a) Maintenance of laboratory and workstation cleanliness and organization
Basic Qualifications:
  • AS, BA or BS in science related field
  • 2-10 years general laboratory experience with significant hands-on laboratory work demonstrating mastery of micro-pipetting, sample manipulation in small tubes and multi-well plates, SDS-PAGE; knowledgeable about and comfortable using other basic lab equipment (e.g. pH meter, balances, centrifuges); proficient making basic calculations, e.g. for making standard buffers from dry chemical ingredients or liquid stock solutions.
  • 1-2 years experience purifying proteins from E. coli, insect and/or mammalian hosts; protein expression experience is a plus
  • 1-2 years experience with modern Akta Pure chromatography system (FPLC) using affinity-capture and SEC chromatography steps
  • 1-2 years experience with preparing and analyzing samples with mass spectrometry (e.g. TOF MS); interpretation of MS data is a plus
  • Ability to follow established laboratory protocols and adhere to data standards; attention to detail and careful execution of laboratory tasks are essential to our team
  • Strong written and oral communication skills
  • Proficient in Microsoft Excel, Word, PowerPoint, LIMS; experience with electronic notebooks
  • Must work well in a team environment and be capable of m
Employee Value Proposition:
The person in this role will work in a great working environment and gain exposure to many areas of the company.
Red Flags:
  • No laboratory experience
  • No industry experience (Only academic experience)
Interview process:
Video Skype Panel Interview
We invite qualified candidates to send your resume to resumes@3keyconsulting.com.  If you decide that you’re not interested in pursuing this particular position, please feel free to take a look at the other positions on our website www.3keyconsulting.com/careers. You are also welcome to share this opportunity with anyone you think might be interested in applying for this role.
3KC Talent Acquisition Team
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