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Associate Scientist (JP8485)

South San Francisco,, CA · Biotech/Pharmaceutical
Job Title: Associate Scientist (JP8485)
Location: South San Francisco, CA 94080
Employment Type: Contract
Duration: 12 months with likely extensions
Job posting date: 4.15.2021
Note: Onsite Essential. Must be Local
3 Key Consulting is hiring a Associate Scientist for a consulting engagement with our direct client, a leading global bio-pharmaceutical company.
Job Summary:

To underpin our commitment to bring safe and transformative medicines to patients, we are growing our highly innovative Molecular and Cellular Translational Safety group at the client. Our mission is to transform human risk assessment to optimize the discovery and development of vital therapeutics that improve patients' lives. To achieve this, we are applying a variety of human in vitro approaches (including human genetics along with cellular, molecular and structural biology techniques) to develop assays that can predict or elucidate mechanisms leading to drug safety issues. We are seeking a talented Associate Scientist with expertise in biochemistry and cell biology to join our growing group. The successful candidate will play a hands-on role in the lab.

Key responsibilities:
  • Drive wet laboratory biochemistry and cell biology efforts focused on a) understanding the impact of candidate therapeutics on the activity of a variety of proteins and/or cellular functions, b) developing new biochemical or cellular assays to use in drug safety screening.
  • Design, execute and troubleshoot a variety of biochemical and biophysical assays and approaches.
  • Interface with scientists in medicinal chemistry, protein chemistry, and therapeutic discovery groups to develop tagged reagents or novel in vitro systems.
  • Analyze, interpret, meticulously document and present data in group and department meetings.
  • Assess new technologies and approaches that can be applied to further our research goals

    Basic Qualifications:
  • Master’s degree and 2 years of Scientific experience OR
  • Bachelor’s degree and 4 years of Scientific experience

    Preferred Qualifications:
  • Master’s Degree with 3+ years of scientific experience
  • Demonstrated expertise in a variety of biochemical approaches to understand protein function with a particular focus on characterizing their inhibition or activation by small and large molecules.
  • Experience in working with a variety of cell cultures, such as primary cells or various human cell lines, along with expertise in cellular functional endpoint measures in these systems.
  • Experience in the synthesis and utility of tagged small molecule probes for the purification of interacting proteins.
  • Proficiency with a variety of other molecular and cellular biology and biomarker techniques including PCR, molecular cloning, sequence analysis, ELISA, western blot etc.
  • Ability to work independently in experimental design, execution and data analysis
  • Comfort in working in a highly interactive and vibrant environment and a passion for teamwork

Top Must have Skill Sets:
  • Cell culture-5-7 years of experience
  • Western blot-3 - 5 years of experience
  • PCR, DNA/RNA extraction-2-3 years of experience
Day-To-Day Responsibilities:
  • Culture human cell lines for proteomics work to support new modalities (PROTAC and siRNA)
  • Support safety issue resolution for our pipeline projects, using various biochemical approaches such as western blot, and PCR.
  • Work in a team, by contributing experimental data to guide screening strategy for new modalities such as siRNA.
Employee Value Proposition: Potential for extension. Experience with a vast global company.
Red Flags:
1. Lack of productivity/hard work
2. Lack of timeliness
3. Lack of team spirits
4. Lack of communication
Interview Process
Two  Webex interviews with manager.
Manager  will also need to call candidate’s reference(s), up to 2.
We invite qualified candidates to send your resume to resumes@3keyconsulting.com. If you decide that you’re not interested in pursuing this position, please feel free to look at other positions on our website www.3keyconsulting.com. You are welcome to also share this posting with anyone you think might be interested in applying for this role.
3KC Talent Acquisition Team
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